Blondie (Clint Eastwood) and Tuco (Eli Wallach) are gunmen who admire each other professionally but dislike each other personally. Encountering a group of dying soldiers, Tuco learns the location of the graveyard where a Confederate treasure is buried, while Blondie learns the identity of the exact grave. Joined by mercenary drifter Angel Eyes (Lee Van Cleef), they cross the desert, each of the desperadoes knowing half the secret and each focusing his squinty eyes on the $200,000 bounty.

In a classic that puts style above substance, Italian director Sergio Leone uses vivid Cinemascope imagery to depict a bleak and bloody American West in this final installment of his collaboration with Clint Eastwood in the Man with No Name Trilogy. A prototype for the so-called Spaghetti Western genre, the film solidified Eastwood's position as a major international star with his stoic, brooding presence. Cinematographer Tonino Delli Colli's stunning visuals are a match for the vivacious Ennio Morricone score, one of the most recognizable in all of cinema. Although the film was not released in the United States until 1967, it was produced and released internationally in 1966.